2023 AMLI Annual Meeting
Scientific Lecture Program

Friday, August 11 to Monday, August 14, 2023

This meeting will be held in-person in Seattle, Washington

The Association of Medical Laboratory Immunologists is approved as a provider of continuing education
programs in the clinical laboratory sciences by the ASCLS P.A.C.E. ® Program.

Friday, August 11, 2023

7:00-8:15
Hosted by
The Binding Site, a part of Thermo Fisher Scientific
Introduction to EXENT, a point-and-click Mass Spec Solution for Identifying and
Quantifying Monoclonal Immunoglobulins
Presenters:
Stephen Harding, Ph.D., Chief Scientific Officer
Jill Pauli, Ph.D.,  Director, Scientific Affairs

PLENARY SESSION 1
Updates on the Inborn Errors of Immunity
Chairs: Roshini Sarah Abraham, Ph.D., D(ABMLI), Nationwide Children’s Hospital and
Hemant Joshi, Ph.D., Mount Sinai Hospital

8:35
Harmonization Efforts in Reporting and Nomenclature in Newborn Screening for SCID
Amy Gaviglio, M.S., CGC, Connetics Consulting/APHL/CDC

9:20
Updates in the Inborn Errors of Immunity (Immunodeficiencies and Immune Dysregulation)
Eric J. Allenspach, M.D., Ph.D., Seattle Children’s Research Institute

10:05
Break

10:20
Functional Validation of Immunologically Relevant Variants
Sam Chiang, Ph.D., Cincinnati Children’s Hospital and University of Cincinnati

11:05
A Clinical Perspective on Diagnostic Challenges in the Inborn Errors of Immunity
Karin Chen, M.D., University of Washington and Seattle Children’s Hospital

12:00-1:30
Luncheon Seminar hosted by EUROIMMUN US
From Diagnosis to Empowerment:  A Patient’s Mission to Educate on Early Diagnosis
Speaker: Sarah DiMilla
Host: Dr. Iswariya (Ishu) Venkataraman, Director of Scientific Affairs

PLENARY SESSION 2
Emerging Vector-Borne Infections: Pathogens, Climate and What is Being Done
to Combat Them
Chair: John Schmitz, Ph.D., University of North Carolina at Chapel Hill and
Caleb Cornaby, Ph.D, F(ACHI), Children’s Hospital Los Angeles

2:00
Emerging Tick-Borne Infections in the United States
Ross M. Boyce, M.D., M.Sc., University of North Carolina School of Medicine (Virtual)

2:45
Emerging Arboviral Infections
Natasha Tilston-Lunel, Ph.D., Indiana University School of Medicine (Virtual)

3:30
The Impact of Climate Change on Vector-Borne Infections
Kristie L. Ebi, Ph.D., MPH, University of Washington

4:15
The Growing Challenge of Vector-Borne Diseases and the U.S. Plan to Address the Challenge
Aaron C. Brault, Ph.D., U.S. Centers for Disease Control and Prevention

5:00 – 7:00
Meet the Exhibitors – Poster Session Reception
Sponsored by Kronus

Saturday, August 12, 2023

7:30
Continental Breakfast
Meet the Exhibitors
Committee Meetings

PLENARY SESSION 3
Precision Medicine in Autoimmunity:  Challenges, Opportunities and Motivation
Chairs:  Anne Tebo, Ph.D., Mayo Clinic and Mark H. Wener, M.D., UW Medical Center – Roosevelt

8:30
Challenges and Opportunities in Proficiency Testing for Autoimmune Serologic Tests
Susan L. Fink, M.D., Ph.D., University of Washington

9:15
The Role of Autoantibodies in the Diagnosis and Prognostication of Primary Biliary Cholangitis
Christopher L. Bowlus, M.D., University of California, Davis

10:00
Break
Meet the Exhibitors
Committee Meetings

10:30
The Properties of Anti-DNA Antibodies in Normal and Aberrant Immunity
David Pisetsky, M.D., Ph.D., Duke University Medical Center and VA Medical Center

11:15
Rheumatoid Arthritis Autoantibodies in the Laboratory and in Clinical Practice:
A North European Perspective
Johan Rönnelid, M.D., Ph.D., Uppsalla University Hospital

12:00-1:30
Luncheon Seminar hosted by WERFEN
The Role of Anti-HMGCR Autoantibodies in Myositis
Lisa Christopher-Stine, M.D., M.P.H., Johns Hopkins University School of Medicine

2:00
NETER AWARD LECTURE
Mark H. Wener, M.D.
An Approach To Harmonize Autoantibody Testing:
Calibration & Harmonization Adjustment via Population Interrogation (CHAPI)

3:00 – 3:45
Award Presentations

3:45-4:15
Business Meeting

Sunday, August 13, 2023

7:30
Continental Breakfast
Meet the Exhibitors
Committee Meetings

PLENARY SESSION 4
The Renaissance of Complements and Complement Therapeutics
Chairs:  Ashley Frazer-Abel, Ph.D., Exsera BioLabs, University of Colorado School of Medicine and
Vijayalakshmi Nandakumar, Ph.D., DABCC, University of Utah School of Medicine

8:30
Tipping the Balance: Role of Complements in Disease and Therapy
Vijayalakshmi Nandakumar, Ph.D., DABCC, University of Utah School of Medicine

9:15
Looking at the Glomeruli Through the Eyes of the Complement System
Abbal Koirala, M.D., University of Washington and UW-Harborview Medical Center

10:00
Break
Meet the Exhibitors

10:15
Defining the Complement Rheostat in Inflammatory (Liver) Diseases
Rebecca L. McCullough, Ph.D., Skaggs School of Pharmacy, University of Colorado Anschutz Medical Campus

11:00
Challenges and Future of Complement Testing
Ashley Frazer-Abel, Ph.D., D(ABMLI), Exsera BioLabs, University of Colorado School of Medicine

12:00-1:30

Luncheon Seminar hosted by THERMO FISHER SCIENTIFIC
Practical Application of Likelihood Ratios within the Clinical Laboratory
Veena Joy, M.Sc., Ph.D., Thermo Fisher
Johan Rönnelid, M.D., Ph.D., Uppsalla University Hospital

Monday, August 14, 2023

7:00-8:15
Breakfast Seminar
OPEN AND AVAILABLE

7:30
Continental Breakfast

PLENARY SESSION 5
Methods, LDT and Regulation
Chairs: Lusia Sepiashvili, Ph.D., The Hospital for Sick Children,
Abdulrahman Saadalla, M.B., B.Ch., University of Utah, and
Maria Alice V. Willrich, Ph.D., Mayo Clinic

8:30
FDA Regulation of Laboratory Developed Tests – A Whirlwind Tour
Shannon A. Bennett, M.S., MBA, Mayo Clinic

9:15
Laboratory Developed Tests in AMC’s – Medical Practice or Medical Device?
Eric Q. Konnick, M.D., M.S., University of Washington

10:00
Break

10:30
Uncovering the Depths of the Human Proteome:
Antibody-based Technologies for Ultrasensitive Multiplexed Protein
Detection and Quantification
Vanthany Kulasingam, Ph.D., FCACB, University Health Network and University of Toronto

11:15
CyTOF Applications for Clinical Immunology:  Maximizing your Sample Potential
Caroline Duault, PharmD, Ph.D., Stanford University School of Medicine

12:00 noon
Conclusion of Meeting