7:30 am

Continental Breakfast

8:30-8:35 am

Opening Remarks
Evan Ntrivalas, M.D., Ph.D., AMLI President

New Roles for an Old Entity: the Complement System

Ashley Frazer-Abel, Ph.D. and Maria Alice V. Willrich, Ph.D

8:35-9:10 am

Introduction to the Complement System and Laboratory Testing
Maria Alice V. Willrich, Ph.D., Mayo Clinic

9:10-9:50 am

C3 Glomerulopathies – New Breakthroughs and Old Challenges
Joshua M.Thurman, M.D., University of Colorado School of Medicine

9:50-10:10 am


10:10-10:50 am

The Role of Complement in Atypical Hemolytic Uremic Syndrome
Meera Sridharan, M.D., Ph.D., Mayo Clinic

10:50-11:20 am

Complement Therapeutics: Reality and Perspectives
Ashley Frazer-Abel, Ph.D., D(ABMLI), Exsera BioLabs, University of Colorado School of Medicine

11:20 am  

Case Presentation and Round-Table Discussion
Moderated by Ashley Frazer-Abel, Ph.D. and Maria Alice V. Willrich, Ph.D.

12:00-1:30 PM  

Luncheon Seminar sponsored by Inova Diagnostics
Systemic Autoimmune Diseases:

The New Clinical Context and Implications for Testing
Michael Mahler, Ph.D., Inova Diagnostics

Updates in Autoimmunity: ANCA

M. Qasim Ansari, M.D. and Colleen J. Lewis, Ph.D., D(ABMLI)

2:00-2:15 pm


ANCA-Associated Vasculitis: Introduction and a Case Study
Colleen J. Lewis, Ph.D., D(ABMLI), Quest Diagnostics Nichols Institute

2:15-3:05 pm  

Challenges in Laboratory Testing of ANCA : Presentation of a Study Demonstrating Extreme Diversity of ANCA Testing in the US
M. Qasim Ansari, M.D., Cleveland Clinic Lerner College of Medicine

3:05-3:15 pm


3:15-4:15 pm

Update on ANCA-Associated Vasculitis
Carol Langford, M.D., MHS, Center for Vasculitis Care and Research, Cleveland Clinic

4:15-5:00 pm

Panel Discussion and Question and Answer Session
Colleen J. Lewis, Ph.D., D(ABMLI), M. Qasim Ansari, M.D., and Carol Langford, M.D., MHS

5:00-7:00 pm

Meet the Exhibitors – Poster Session Reception

Monday, August 14

7:00-8:15 AM

Breakfast Seminar sponsored by Bio-Rad Laboratories
Shifting Gears for Syphilis Testing: Forward or Reverse; Manual or Automatic
Thomas S. Alexander, Ph.D., D(ABMLI), Summa Health

7:30 am

Continental Breakfast, EXHIBITS OPEN

Vaccination and Vaccine Response Assessment
in Primary and Acquired Immune Deficiencies

Chaired by:
Vijaya N. Knight, M.D., Ph.D., and Roshini Abraham, Ph.D.

8:30-9:00 am

Challenges in Primary Immunodeficiency: The Good, the Bad, the Evil
Erwin W. Gelfand, M.D., National Jewish Health

9:00-9:30 am

Understanding and Assessing the Vaccine Response in Immunocompromised Patients
Pia J. Hauk, M.D., National Jewish Health

9:30-10:00 am

Live Attenuated Vaccines in Cellular Immune Deficiency Post Bone Marrow Transplant
Elena Hsieh, M.D., University of Colorado Denver

10:00-10:30 am


10:30-11:00 am

Can the Measurement of Typhim Vi IgG Be Used to Assess the Response to
Polysaccharide Vaccines?
Antony Parker, Ph.D., The Binding Site Group

11:30-12:00 am

Panel Discussion and Q/A
Moderated by Vijaya Knight, M.D., Ph.D. and Roshini Abraham, Ph.D.

12:00-1:30 pm

Luncheon Seminar sponsored by Thermo Fisher Scientific
A Realistic Path to Achieving High Quality ANA/ENA Results, Efficiency Gains,
and Clinician Satisfactio
Ifor Williams, M.D., Ph.D., Emory University

2:00-3:00 pm 

Erwin Neter Award Lecture
Walking the Complement Pathways to Create a Unique Laboratory

Patricia B. Giclas, Ph.D., National Jewish Health

3:00-3:30 pm


Abstract Award Presentations

3:30-4:00 pm


AMLI Business Meeting for all AMLI Members 

4:00-6:00 pm

Meet the Exhibitors Poster Session Reception

6:00 pm

Depart for Annual Dinner at
Palettes Restaurant at the Denver Art Museum

Buses will depart between 6:00 and 6:15

Tuesday, August 15

7:00-8:15 am

Breakfast Seminar sponsored by Thermo Fisher Scientific.
Revised International Consensus Recommendation on Testing of
Anti-Neutrophil Cytoplasm Antibodies (ANCA) in Small Vessel Vasculitis:
Evaluation of ANCA Testing by Antigen Specific Assays

Elena Csernok, M.D., former head of Vasculitis Diagnostic and Research Unit at the Department of Rheumatology and Immunology, Klinikum Bad Bramstedt, University of Lübeck; currently, Reference Laboratory for Vasculitis Autoimmune Serology, Clinic for Internal Medicine, Rheumatology and Immunology, medius KLINIK KIRCHHEIM, Academic Lehr Hospital, University Tübingen, Germany

7:30 am

Continental Breakfast, Committee Meetings, EXHIBITS OPEN

Aging and the Immune System

Chaired by:
Amir A. Sadighi Akha, M.D., D.Phil. and Lisa K. Peterson, Ph.D.

8:30-9:10 am

Aging and the Immune System: An Overview
Amir A. Sadighi Akha, M.D., D.Phil., Mayo Clinic

9:10-10:00 am

Novel Pathways of Age-Enhanced Inflammation
Daniel R. Goldstein, M.D., University of Michigan Medical School

10:00-10:20 am  


10:20-11:10 am  

T Cell Aging – Mechanisms and Biomarkers
Jörg J. Goronzy, M.D., Ph.D., Stanford University School of Medicine


Aging, Inflammation and Poor B Cell Response: How Response to Vaccination
Decreases in Older and Obese Adults

Bonnie B. Blomberg, Ph.D., University of Miami Miller School of Medicine

12:00-1:30 pm

Luncheon Seminar hosted by Euroimmun US
Neurology Diagnostics

Stanley J. Naides, MD., FACP, FACR, Quest Diagnostics


Wednesday, August 16

7:30 am  

Continental Breakfast
Committee Meetings

The Molecular Revolution in the Clinical Laboratory and Beyond

Chaired by:
Kevin Goudy, Ph.D.and Eric T. Weimer, Ph.D., D(ABMLI)

8:30-9:15 am

Molecular Diagnostics in the Clinical Laboratory: Win, Lose or Draw
Kevin Goudy, Ph.D., CSI Laboratories

9:15-10:00 am

Antibody Repertoire and Influenza Immunity
Ian A. York, DVM, M.Sc., Ph.D., NCIRD, Centers for Disease Control and Prevention

10:00-10:30 am


10:30 am

Gene Therapy in the Treatment of Primary Immune Deficiencies
Caroline Kuo, M.D., UCLA Medical Center, Los Angeles, CA

10:30-11:15 am  

Clonal Tracking of Genetically Engineered Human Immune and Hematopoietic Cells
Through Integration Sites Analysis

Luca Biasco, Ph.D., Dana-Farber/Boston Children’s Cancer and Blood Disorders Center; UCL Great Ormond Street Institute of Child Health


Cell-free DNA as a Transplant Rejection Biomarker
Eric T. Weimer, Ph.D., D(ABMLI), University of North Carolina School of Medicine

12:00 noon

Closing Remarks